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BMI1–UBR5 axis regulates transcriptional repression at damaged chromatin
BMI1 is a component of the Polycomb Repressive Complex 1 (PRC1), which plays a key role in maintaining epigenetic silencing during development. BMI1 also participates in gene silencing during DNA damage response, but the precise downstream function of BMI1 in gene silencing is unclear. Here we ident...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056041/ https://ncbi.nlm.nih.gov/pubmed/27647897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610735113 |
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