BMI1–UBR5 axis regulates transcriptional repression at damaged chromatin

BMI1 is a component of the Polycomb Repressive Complex 1 (PRC1), which plays a key role in maintaining epigenetic silencing during development. BMI1 also participates in gene silencing during DNA damage response, but the precise downstream function of BMI1 in gene silencing is unclear. Here we ident...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Sanchez, Anthony, De Vivo, Angelo, Uprety, Nadima, Kim, Jonghwan, Stevens, Stanley M., Kee, Younghoon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056041/
https://ncbi.nlm.nih.gov/pubmed/27647897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610735113
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