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Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas
Osteosarcomas are characterized by highly disrupted genomes. Although osteosarcomas lack common fusions, we find evidence of many tumour specific gene-gene fusion transcripts, likely due to chromosomal rearrangements and expression of transcription-induced chimeras. Most of the fusions result in out...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344567/ https://ncbi.nlm.nih.gov/pubmed/30674975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36840-z |
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