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PM-14 MODELING GBM IN MICE USING THE CRISPR NUCLEASE SYSTEM TO FUNCTIONALLY VALIDATE NOVEL CANDIDATE DRIVER GENES AND TEST NEW THERAPIES
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor and has a dismal survival rate of less than 20% in pediatric patients and less than 5% in adults. Identifying and functionally validating driver genes is needed to develop novel therapies to better treat GBM. To this end,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218475/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou268.14 |
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