Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma

Osteosarcoma is the most common primary bone tumor, with metastatic disease responsible for most treatment failure and patient death. A forward genetic screen utilizing Sleeping Beauty mutagenesis in mice previously identified potential genetic drivers of osteosarcoma metastasis, including Slit-Robo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marko, Tracy A., Shamsan, Ghaidan A., Edwards, Elizabeth N., Hazelton, Paige E., Rathe, Susan K., Cornax, Ingrid, Overn, Paula R., Varshney, Jyotika, Diessner, Brandon J., Moriarity, Branden S., O’Sullivan, M. Gerard, Odde, David J., Largaespada, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155223/
https://ncbi.nlm.nih.gov/pubmed/27966608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39059
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