Structural insights into the Slit-Robo complex

Slits are large multidomain leucine-rich repeat (LRR)-containing proteins that provide crucial guidance cues in neuronal and vascular development. More recently, Slits have been implicated in heart morphogenesis, angiogenesis, and tumor metastasis. Slits are ligands for the Robo (Roundabout) recepto...

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Detalhes bibliográficos
Main Authors: Morlot, Cecile, Thielens, Nicole M., Ravelli, Raimond B. G., Hemrika, Wieger, Romijn, Roland A., Gros, Piet, Cusack, Stephen, McCarthy, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975871/
https://ncbi.nlm.nih.gov/pubmed/17848514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705310104
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