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Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression
Vitiligo is an autoimmune disease in which melanocyte destruction causes skin depigmentation, with 49 loci known from previous GWAS. Aiming to define vitiligo subtypes, we discovered that age-of-onset is bimodal; one-third of cases have early onset (mean 10.3 years) and two-thirds later onset (mean...
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| Vydáno v: | Nat Commun |
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| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344500/ https://ncbi.nlm.nih.gov/pubmed/30674883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08337-4 |
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