Endothelial Cell-Specific Overexpression of Endothelial Nitric Oxide Synthase in Ins2Akita Mice Exacerbates Diabetic Nephropathy

AIM/HYPOTHESIS: Endothelial dysfunction due to impaired endothelial nitric oxide synthase (eNOS) activity is a key factor implicated in the progression of diabetic nephropathy. Previous studies demonstrated that global deficiency of eNOS in diabetic mice exacerbated renal lesions. In this study we i...

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Gepubliceerd in:J Diabetes Complications
Hoofdauteurs: Natarajan, Mohan, Habib, Samy, Reddick, Robert L., Delma, Caroline R., Manickam, Krishnan, Prihoda, Thomas J., Werner, Sherry L., Mohan, Sumathy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344355/
https://ncbi.nlm.nih.gov/pubmed/30424931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdiacomp.2018.10.003
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