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Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2(Akita/+) Mice
Endothelial-mesenchymal transition (EndMT) drives endothelium to contribute to normal development and disease processes. Here, we report that EndMTs occur in the diabetic endothelium of Ins2(Akita/wt) mouse, and show that induction of sex determining region Y-box 2 (Sox2) is a mediator of excess BMP...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5148029/ https://ncbi.nlm.nih.gov/pubmed/27936229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167936 |
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