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Dynamic Actin Reorganization and Vav/Cdc42-dependent Actin Polymerization Promote Macrophage Aggregated LDL Uptake and Catabolism
OBJECTIVE: During atherosclerosis, low density lipoproteins (LDL) accumulate in the arteries, where they become modified, aggregated and retained. Such deposits of aggregated LDL (agLDL) can be recognized by macrophages, which attempt to digest and clear them. AgLDL catabolism promotes internalizati...
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| Veröffentlicht in: | Arterioscler Thromb Vasc Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344252/ https://ncbi.nlm.nih.gov/pubmed/30580573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.312087 |
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