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Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally

The sustained expression of the MAFB transcription factor in human islet β-cells represents a distinct difference in mice. Moreover, mRNA expression of closely related and islet β-cell–enriched MAFA does not peak in humans until after 9 years of age. We show that the MAFA protein also is weakly prod...

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Publicado en:Diabetes
Main Authors: Cyphert, Holly A., Walker, Emily M., Hang, Yan, Dhawan, Sangeeta, Haliyur, Rachana, Bonatakis, Lauren, Avrahami, Dana, Brissova, Marcela, Kaestner, Klaus H., Bhushan, Anil, Powers, Alvin C., Stein, Roland
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341297/
https://ncbi.nlm.nih.gov/pubmed/30425060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0903
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