The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells

Analysis of MafB(−/−) mice has suggested that the MAFB transcription factor was essential to islet α- and β-cell formation during development, although the postnatal physiological impact could not be studied here because these mutants died due to problems in neural development. Pancreas-wide mutant...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Conrad, Elizabeth, Dai, Chunhua, Spaeth, Jason, Guo, Min, Cyphert, Holly A., Scoville, David, Carroll, Julie, Yu, Wei-Ming, Goodrich, Lisa V., Harlan, David M., Grove, Kevin L., Roberts, Charles T., Powers, Alvin C., Gu, Guoqiang, Stein, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675799/
https://ncbi.nlm.nih.gov/pubmed/26554594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00285.2015
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