Gestational Diabetes Mellitus From Inactivation of Prolactin Receptor and MafB in Islet β-Cells

β-Cell proliferation and expansion during pregnancy are crucial for maintaining euglycemia in response to increased metabolic demands placed on the mother. Prolactin and placental lactogen signal through the prolactin receptor (PRLR) and contribute to adaptive β-cell responses in pregnancy; however,...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Banerjee, Ronadip R., Cyphert, Holly A., Walker, Emily M., Chakravarthy, Harini, Peiris, Heshan, Gu, Xueying, Liu, Yinghua, Conrad, Elizabeth, Goodrich, Lisa, Stein, Roland W., Kim, Seung K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955982/
https://ncbi.nlm.nih.gov/pubmed/27217483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1527
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