The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth

The large Maf transcription factors, MafA and MafB, are expressed with distinct spatial–temporal patterns in rodent islet cells. Analysis of Mafa(−/−) and pancreas-specific Mafa(∆panc) deletion mutant mice demonstrated a primary role for MafA in adult β-cell activity, different from the embryonic im...

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Bibliographische Detailangaben
Hauptverfasser: Hang, Yan, Yamamoto, Tsunehiko, Benninger, Richard K.P., Brissova, Marcela, Guo, Min, Bush, Will, Piston, David W., Powers, Alvin C., Magnuson, Mark, Thurmond, Debbie C., Stein, Roland
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2014
Schlagworte:
Islet Studies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030115/
https://ncbi.nlm.nih.gov/pubmed/24520122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1001
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