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Y-27632 preconditioning enhances transplantation of human-induced pluripotent stem cell-derived cardiomyocytes in myocardial infarction mice

AIMS : The effectiveness of cell-based treatments for regenerative myocardial therapy is limited by low rates of cell engraftment. Y-27632 inhibits Rho-associated protein kinase (ROCK), which regulates the cytoskeletal changes associated with cell adhesion, and has been used to protect cultured cell...

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Bibliografiske detaljer
Udgivet i:Cardiovasc Res
Main Authors: Zhao, Meng, Fan, Chengming, Ernst, Patrick J, Tang, Yawen, Zhu, Hanxi, Mattapally, Saidulu, Oduk, Yasin, Borovjagin, Anton V, Zhou, Lufang, Zhang, Jianyi, Zhu, Wuqiang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341224/
https://ncbi.nlm.nih.gov/pubmed/30107391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy207
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