C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution

Single-cell transcriptomic profiling is a powerful tool to explore cellular heterogeneity. However, most of these methods focus on the 3′-end of polyadenylated transcripts and provide only a partial view of the transcriptome. We introduce C1 CAGE, a method for the detection of transcript 5′-ends wit...

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Publicado no:Nat Commun
Main Authors: Kouno, Tsukasa, Moody, Jonathan, Kwon, Andrew Tae-Jun, Shibayama, Youtaro, Kato, Sachi, Huang, Yi, Böttcher, Michael, Motakis, Efthymios, Mendez, Mickaël, Severin, Jessica, Luginbühl, Joachim, Abugessaisa, Imad, Hasegawa, Akira, Takizawa, Satoshi, Arakawa, Takahiro, Furuno, Masaaki, Ramalingam, Naveen, West, Jay, Suzuki, Harukazu, Kasukawa, Takeya, Lassmann, Timo, Hon, Chung-Chau, Arner, Erik, Carninci, Piero, Plessy, Charles, Shin, Jay W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6341120/
https://ncbi.nlm.nih.gov/pubmed/30664627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08126-5
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