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A framework for identification of on- and off-target transcriptional responses to drug treatment
Owing to safety concerns or insufficient efficacy, few drug candidates are approved for marketing. Drugs already on the market may be withdrawn due to adverse effects (AEs) discovered after market introduction. Comprehensively investigating the on-/off-target effects of drugs can help expose AEs dur...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6879629/ https://ncbi.nlm.nih.gov/pubmed/31772269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54180-4 |
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