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Recombinant tri-segmented Pichinde virus as a novel live viral vaccine platform

Pichinde virus (PICV) is a nonpathogenic arenavirus with a bi-segmented RNA genome (L and S segments) that encodes four viral genes. We have developed a reverse genetics system to generate recombinant tri-segmented PICV (rP18tri) that packages three RNA segments (L, S1, and S2) and can encode up to...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Dhanwani, Rekha, Ly, Hinh, Liang, Yuying
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340294/
https://ncbi.nlm.nih.gov/pubmed/28374249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6869-5_10
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