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In Vitro and In Vivo Characterizations of Pichinde Viral Nucleoprotein Exoribonuclease Functions

Arenaviruses cause severe hemorrhagic fever diseases in humans, and there are limited preventative and therapeutic measures against these diseases. Previous structural and functional analyses of arenavirus nucleoproteins (NPs) revealed a conserved DEDDH exoribonuclease (RNase) domain that is importa...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Huang, Qinfeng, Shao, Junjie, Lan, Shuiyun, Zhou, Yanqin, Xing, Junji, Dong, Changjiang, Liang, Yuying, Ly, Hinh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468471/
https://ncbi.nlm.nih.gov/pubmed/25878103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00009-15
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