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In Vitro and In Vivo Characterizations of Pichinde Viral Nucleoprotein Exoribonuclease Functions

Arenaviruses cause severe hemorrhagic fever diseases in humans, and there are limited preventative and therapeutic measures against these diseases. Previous structural and functional analyses of arenavirus nucleoproteins (NPs) revealed a conserved DEDDH exoribonuclease (RNase) domain that is importa...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Huang, Qinfeng, Shao, Junjie, Lan, Shuiyun, Zhou, Yanqin, Xing, Junji, Dong, Changjiang, Liang, Yuying, Ly, Hinh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468471/
https://ncbi.nlm.nih.gov/pubmed/25878103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00009-15
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