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Assays to Demonstrate the Roles of Arenaviral Nucleoproteins (NPs) in Viral RNA Synthesis and in Suppressing Type I Interferon

Arenaviruses, such as Lassa fever virus (LASV) and Pichinde virus (PICV), are enveloped viruses with a bi-segmented ambisense RNA genome. The large (L) genomic segment encodes the Z matrix protein and the L RNA-dependent RNA polymerase, whereas the small (S) genomic segment encodes the nucleoprotein...

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Publicado en:Methods Mol Biol
Autores principales: Huang, Qinfeng, Shao, Junjie, Liang, Yuying, Ly, Hinh
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6391876/
https://ncbi.nlm.nih.gov/pubmed/28986834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6981-4_13
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