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Recombinant tri-segmented Pichinde virus as a novel live viral vaccine platform

Pichinde virus (PICV) is a nonpathogenic arenavirus with a bi-segmented RNA genome (L and S segments) that encodes four viral genes. We have developed a reverse genetics system to generate recombinant tri-segmented PICV (rP18tri) that packages three RNA segments (L, S1, and S2) and can encode up to...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Methods Mol Biol
Main Authors: Dhanwani, Rekha, Ly, Hinh, Liang, Yuying
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340294/
https://ncbi.nlm.nih.gov/pubmed/28374249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6869-5_10
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