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Allosteric modulation of JNK docking-site interactions with ATP-competitive inhibitors
The c-Jun N-terminal kinases (JNKs) play a wide variety of roles in cellular signaling processes, dictating important, and even divergent, cellular fates. These essential kinases possess docking surfaces distal to their active sites that interact with diverse binding partners, including upstream act...
Enregistré dans:
| Publié dans: | Biochemistry |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6338552/ https://ncbi.nlm.nih.gov/pubmed/30211540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00776 |
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