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Multiplication of the SNCA locus exacerbates neuronal nuclear aging

Human-induced Pluripotent Stem Cell (hiPSC)-derived models have advanced the study of neurodegenerative diseases, including Parkinson’s disease (PD). While age is the strongest risk factor for these disorders, hiPSC-derived models represent rejuvenated neurons. We developed hiPSC-derived Aged dopami...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Tagliafierro, Lidia, Zamora, Madison Elena, Chiba-Falek, Ornit
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337700/
https://ncbi.nlm.nih.gov/pubmed/30304516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy355
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