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Effects of mavoglurant on visual attention and pupil reactivity while viewing photographs of faces in Fragile X Syndrome

BACKGROUND: Numerous preclinical studies have supported the theory that enhanced activation of mGluR5 signaling, due to the absence or reduction of the FMR1 protein, contributes to cognitive and behavioral deficits in patients with fragile X syndrome (FXS). However multiple phase 2 controlled trials...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hessl, David, Harvey, Danielle, Sansone, Stephanie, Crestodina, Crystal, Chin, Jamie, Joshi, Reshma, Hagerman, Randi J., Berry‐Kravis, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336311/
https://ncbi.nlm.nih.gov/pubmed/30653533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209984
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