Effects of mavoglurant on visual attention and pupil reactivity while viewing photographs of faces in Fragile X Syndrome

BACKGROUND: Numerous preclinical studies have supported the theory that enhanced activation of mGluR5 signaling, due to the absence or reduction of the FMR1 protein, contributes to cognitive and behavioral deficits in patients with fragile X syndrome (FXS). However multiple phase 2 controlled trials...

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Publicado en:PLoS One
Autores principales: Hessl, David, Harvey, Danielle, Sansone, Stephanie, Crestodina, Crystal, Chin, Jamie, Joshi, Reshma, Hagerman, Randi J., Berry‐Kravis, Elizabeth
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336311/
https://ncbi.nlm.nih.gov/pubmed/30653533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209984
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