Effects of mavoglurant on visual attention and pupil reactivity while viewing photographs of faces in Fragile X Syndrome

BACKGROUND: Numerous preclinical studies have supported the theory that enhanced activation of mGluR5 signaling, due to the absence or reduction of the FMR1 protein, contributes to cognitive and behavioral deficits in patients with fragile X syndrome (FXS). However multiple phase 2 controlled trials...

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Publicat a:PLoS One
Autors principals: Hessl, David, Harvey, Danielle, Sansone, Stephanie, Crestodina, Crystal, Chin, Jamie, Joshi, Reshma, Hagerman, Randi J., Berry‐Kravis, Elizabeth
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336311/
https://ncbi.nlm.nih.gov/pubmed/30653533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209984
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