Prepulse Inhibition in Fragile X Syndrome: Feasibility, Reliability, and Implications for Treatment

BACKGROUND: Pharmacological rescue of behavioral, cognitive and synaptic abnormalities in the animal models of fragile X syndrome (FXS) has prompted the initiation of clinical trials of targeted treatments in humans with this condition. Objective, well-validated outcome measures that are reflective...

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Main Authors: Hessl, David, Berry-Kravis, Elizabeth, Cordeiro, Lisa, Yuhas, Jennifer, Ornitz, Edward M., Campbell, Aaron, Chruscinski, Elizabeth, Hervey, Crystal, Long, James M., Hagerman, Randi J.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693303/
https://ncbi.nlm.nih.gov/pubmed/18785205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.30858
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