Statins enhance efficacy of venetoclax in blood cancers

Statins have shown promise as anti-cancer agents in experimental and epidemiologic research. However, any benefit that they provide is likely context-dependent, for example applicable only to certain cancers or in combination with specific anti-cancer drugs. Here, we report that inhibition of HMG-Co...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Lee, J. Scott, Roberts, Andrew, Juarez, Dennis, Vo, Thanh-Trang T., Bhatt, Shruti, Herzog, Lee-or, Mallya, Sharmila, Bellin, Richard J., Agarwal, Suresh K., Salem, Ahmed Hamed, Xu, Tu, Jia, Jia, Li, Lingxiao, Hanna, John R., Davids, Matthew S., Fleischman, Angela G., O’Brien, Susan, Lam, Lloyd T., Leverson, Joel D., Letai, Anthony, Schatz, Jonathan H., Fruman, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336198/
https://ncbi.nlm.nih.gov/pubmed/29899021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaq1240
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