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mTOR inhibition enhances efficacy of dasatinib in ABL-rearranged Ph-like B-ALL
High-risk subtypes of B-cell acute lymphoblastic leukemia (B-ALL) include Philadelphia chromosome-positive (Ph+) B-ALL driven by the BCR-ABL1 oncogene and a more recently identified subtype known as BCR-ABL-like or Ph-like B-ALL. A hallmark of both Ph+ and Ph-like B-ALL is constitutive activation of...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5814232/ https://ncbi.nlm.nih.gov/pubmed/29464092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24020 |
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