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Resistance to mTOR Kinase Inhibitors in Lymphoma Cells Lacking 4EBP1
Inhibitors of the mechanistic target of rapamycin (mTOR) hold promise for treatment of hematological malignancies. Analogs of the allosteric mTOR inhibitor rapamycin are approved for mantle cell lymphoma but have limited efficacy in other blood cancers. ATP-competitive “active-site” mTOR inhibitors...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931643/ https://ncbi.nlm.nih.gov/pubmed/24586420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088865 |
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