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Sphingosine-1-phosphate protects against brain microvascular endothelial junctional protein disorganization and barrier dysfunction caused by alcohol

OBJECTIVE: Sphingosine-1-phosphate (S1P) has known endothelial barrier protective properties, but whether this extends to the blood-brain barrier (BBB) is unclear. We hypothesized that alcohol-induced disruption of brain microvascular endothelial barrier function and junctional protein organization...

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Bibliografiske detaljer
Udgivet i:Microcirculation
Main Authors: Alves, Natascha G., Yuan, Sarah Y., Breslin, Jerome W.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6335152/
https://ncbi.nlm.nih.gov/pubmed/30281888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12506
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