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Sphingosine-1-phosphate protects against brain microvascular endothelial junctional protein disorganization and barrier dysfunction caused by alcohol
OBJECTIVE: Sphingosine-1-phosphate (S1P) has known endothelial barrier protective properties, but whether this extends to the blood-brain barrier (BBB) is unclear. We hypothesized that alcohol-induced disruption of brain microvascular endothelial barrier function and junctional protein organization...
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| Publicado no: | Microcirculation |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6335152/ https://ncbi.nlm.nih.gov/pubmed/30281888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12506 |
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