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The role of sphingosine-1-phosphate in endothelial barrier function

Loss of endothelial barrier function is implicated in the etiology of metastasis, atherosclerosis, sepsis and many other diseases. Studies suggest that sphingosine-1-phosphate (S1P), particularly HDL-bound S1P (HDL–S1P) is essential for endothelial barrier homeostasis and that HDL–S1P may be protect...

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Bibliographic Details
Main Authors: Wilkerson, Brent A., Argraves, Kelley M.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169319/
https://ncbi.nlm.nih.gov/pubmed/25009123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.06.012
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