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Sphingosine-1-Phosphate Treatment Can Ameliorate Microvascular Leakage Caused by Combined Alcohol Intoxication and Hemorrhagic Shock

Fluid resuscitation following hemorrhagic shock is often problematic, with development of prolonged hypotension and edema. In addition, many trauma patients are also intoxicated, which generally worsens outcomes. We directly investigated how alcohol intoxication impacts hemorrhagic shock and resusci...

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Publicat a:Sci Rep
Autors principals: Doggett, Travis M., Alves, Natascha G., Yuan, Sarah Y., Breslin, Jerome W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481382/
https://ncbi.nlm.nih.gov/pubmed/28642485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04157-y
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