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Sphingosine-1-Phosphate Treatment Can Ameliorate Microvascular Leakage Caused by Combined Alcohol Intoxication and Hemorrhagic Shock

Fluid resuscitation following hemorrhagic shock is often problematic, with development of prolonged hypotension and edema. In addition, many trauma patients are also intoxicated, which generally worsens outcomes. We directly investigated how alcohol intoxication impacts hemorrhagic shock and resusci...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Doggett, Travis M., Alves, Natascha G., Yuan, Sarah Y., Breslin, Jerome W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481382/
https://ncbi.nlm.nih.gov/pubmed/28642485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04157-y
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