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Homologous recombination and replication fork protection: BRCA2 and more!

BRCA2 is a breast and ovarian tumor suppressor that guards against genome instability, a hallmark of cancer. Significant progress has been made in improving our understanding of BRCA2 function from biochemical, cellular, and mouse studies. The knowledge gained has been actively exploited to develop...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Symp Quant Biol
Main Authors: Feng, Weiran, Jasin, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333483/
https://ncbi.nlm.nih.gov/pubmed/29686033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2017.82.035006
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