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LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia
Long-term exposure to elevated levels of manganese (Mn) causes manganism, a neurodegenerative disorder with Parkinson’s disease (PD)-like symptoms. Increasing evidence suggests that leucine-rich repeat kinase 2 (LRRK2), which is highly expressed in microglia and macrophages, contributes to the infla...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6333340/ https://ncbi.nlm.nih.gov/pubmed/30645642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210248 |
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