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Crk adaptor proteins mediate actin-dependent T cell migration and mechanosensing induced by the integrin LFA-1

T cell entry into inflamed tissue involves firm adhesion, spreading, and migration of the T cells across endothelial barriers. These events depend on “outside-in” signals through which engaged integrins direct cytoskeletal reorganization. We investigated the molecular events that mediate this proces...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Roy, Nathan H., MacKay, Joanna L., Robertson, Tanner F., Hammer, Daniel A., Burkhardt, Janis K.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333317/
https://ncbi.nlm.nih.gov/pubmed/30538176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aat3178
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