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Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals
Crk family adaptors, consisting of Src homology 2 (SH2) and SH3 protein-binding domains, mediate assembly of protein complexes in signaling. CrkI, an alternately spliced form of Crk, lacks the regulatory phosphorylation site and C-terminal SH3 domain present in CrkII and CrkL. We used gene silencing...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Company of Biologists
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776506/ https://ncbi.nlm.nih.gov/pubmed/19861495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.054627 |
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