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LFA-1 signals to promote actin polymerization and upstream migration in T cells
T cell entry into inflamed tissue requires firm adhesion, cell spreading, and migration along and through the endothelial wall. These events require the T cell integrins LFA-1 and VLA-4 and their endothelial ligands ICAM-1 and VCAM-1, respectively. T cells migrate against the direction of shear flow...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7502589/ https://ncbi.nlm.nih.gov/pubmed/32907931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.248328 |
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