LFA-1 signals to promote actin polymerization and upstream migration in T cells

T cell entry into inflamed tissue requires firm adhesion, cell spreading, and migration along and through the endothelial wall. These events require the T cell integrins LFA-1 and VLA-4 and their endothelial ligands ICAM-1 and VCAM-1, respectively. T cells migrate against the direction of shear flow...

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Bibliografische gegevens
Gepubliceerd in:J Cell Sci
Hoofdauteurs: Roy, Nathan H., Kim, Sarah Hyun Ji, Buffone, Alexander, Blumenthal, Daniel, Huang, Bonnie, Agarwal, Sangya, Schwartzberg, Pamela L., Hammer, Daniel A., Burkhardt, Janis K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502589/
https://ncbi.nlm.nih.gov/pubmed/32907931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.248328
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