3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes

KEY POINTS: Using 3D direct stochastic optical reconstruction microscopy (dSTORM), we developed novel approaches to quantitatively describe the nanoscale, 3D organization of ryanodine receptors (RyRs) in cardiomyocytes. Complex arrangements of RyR clusters were observed in 3D space, both at the cell...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Shen, Xin, van den Brink, Jonas, Hou, Yufeng, Colli, Dylan, Le, Christopher, Kolstad, Terje R., MacQuaide, Niall, Carlson, Cathrine R., Kekenes‐Huskey, Peter M., Edwards, Andrew G., Soeller, Christian, Louch, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Techniques for physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332759/
https://ncbi.nlm.nih.gov/pubmed/30412283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277360
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