3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes

KEY POINTS: Using 3D direct stochastic optical reconstruction microscopy (dSTORM), we developed novel approaches to quantitatively describe the nanoscale, 3D organization of ryanodine receptors (RyRs) in cardiomyocytes. Complex arrangements of RyR clusters were observed in 3D space, both at the cell...

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Vydáno v:J Physiol
Hlavní autoři: Shen, Xin, van den Brink, Jonas, Hou, Yufeng, Colli, Dylan, Le, Christopher, Kolstad, Terje R., MacQuaide, Niall, Carlson, Cathrine R., Kekenes‐Huskey, Peter M., Edwards, Andrew G., Soeller, Christian, Louch, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Techniques for physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6332759/
https://ncbi.nlm.nih.gov/pubmed/30412283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277360
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