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Subcellular Heterogeneity of Ryanodine Receptor Properties in Ventricular Myocytes with Low T-Tubule Density

RATIONALE: In ventricular myocytes of large mammals, not all ryanodine receptor (RyR) clusters are associated with T-tubules (TTs); this fraction increases with cellular remodeling after myocardial infarction (MI). OBJECTIVE: To characterize RyR functional properties in relation to TT proximity, at...

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Detalhes bibliográficos
Main Authors: Biesmans, Liesbeth, Macquaide, Niall, Heinzel, Frank R., Bito, Virginie, Smith, Godfrey L., Sipido, Karin R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192718/
https://ncbi.nlm.nih.gov/pubmed/22022376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025100
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