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Cardiac Resynchronization Therapy Reduces Subcellular Heterogeneity of Ryanodine Receptors, T-Tubules and Ca(2+) Sparks Produced by Dyssynchronous Heart Failure

BACKGROUND: Cardiac resynchronization therapy (CRT) is a major advance for treatment of patients with dyssynchronous heart failure (DHF). However, our understanding of DHF-associated remodeling of subcellular structure and function and their restoration after CRT remains incomplete. METHODS AND RESU...

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Detalhes bibliográficos
Publicado no:Circ Heart Fail
Main Authors: Li, Hui, Lichter, Justin G., Seidel, Thomas, Tomaselli, Gordon F., Bridge, John H. B., Sachse, Frank B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651794/
https://ncbi.nlm.nih.gov/pubmed/26294422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.002352
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