Llwytho...
Small Molecule Targeting of Protein–Protein Interactions through Allosteric Modulation of Dynamics
The protein–protein interaction (PPI) target class is particularly challenging, but offers potential for “first in class” therapies. Most known PPI small molecules are orthosteric inhibitors but many PPI sites may be fundamentally intractable to this approach. One potential alternative is to conside...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Molecules |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
MDPI
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6332300/ https://ncbi.nlm.nih.gov/pubmed/26378508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules200916435 |
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