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Modulating Target Protein Biology Through the Re-mapping of Conformational Distributions Using Small Molecules
Over the last 10 years considerable progress has been made in the application of small molecules to modulating protein-protein interactions (PPIs), and the navigation from “undruggable” to a host of candidate molecules in clinical trials has been well-charted in recent, comprehensive reviews. Struct...
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| Publicado no: | Front Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8129178/ https://ncbi.nlm.nih.gov/pubmed/34017820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.668186 |
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