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Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress
Expansion of a hexanucleotide repeat (HRE), GGGGCC, in the C9ORF72 gene is recognized as the most common cause of familial amyotrophic lateral sclerosis (FALS), frontotemporal dementia (FTD) and ALS-FTD, as well as 5–10% of sporadic ALS. Despite the location of the HRE in the non-coding region (with...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6331062/ https://ncbi.nlm.nih.gov/pubmed/29792928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.05.009 |
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