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The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD

Expansion of a hexanucleotide (GGGGCC) repeat in the gene chromosome 9 open reading frame 72 (C9ORF72) is the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia (FTD). Three non-exclusive mechanisms have been proposed to contribute to the pathology initiated by this genet...

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Bibliografski detalji
Izdano u:Front Mol Neurosci
Glavni autori: Freibaum, Brian D., Taylor, J. Paul
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303742/
https://ncbi.nlm.nih.gov/pubmed/28243191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00035
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