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The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD
Expansion of a hexanucleotide (GGGGCC) repeat in the gene chromosome 9 open reading frame 72 (C9ORF72) is the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia (FTD). Three non-exclusive mechanisms have been proposed to contribute to the pathology initiated by this genet...
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| Veröffentlicht in: | Front Mol Neurosci |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5303742/ https://ncbi.nlm.nih.gov/pubmed/28243191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00035 |
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