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Safety, immunogenicity and protection of A(H3N2) live attenuated influenza vaccines containing wild-type nucleoprotein in a ferret model

Live attenuated influenza vaccines (LAIVs) are promising tools for the induction of broad protection from influenza due to their ability to stimulate cross-reactive T cells against influenza pathogens. One of the major targets for cytotoxic T-cell immunity is viral nucleoprotein (NP), which is relat...

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Detalhes bibliográficos
Publicado no:Infect Genet Evol
Main Authors: Korenkov, Daniil A., Laurie, Karen L., Reading, Patrick C., Carolan, Louise A., Chan, Kok Fei, Isakova-Sivak, Irina I., Smolonogina, Tatiana A., Subbarao, Kanta, Barr, Ian G., Villanueva, Julie, Shcherbik, Svetlana, Bousse, Tatiana, Rudenko, Larisa G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330673/
https://ncbi.nlm.nih.gov/pubmed/29929009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2018.06.019
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