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H7N9 Live Attenuated Influenza Vaccine Is Highly Immunogenic, Prevents Virus Replication, and Protects Against Severe Bronchopneumonia in Ferrets

Avian influenza viruses continue to cross the species barrier, and if such viruses become transmissible among humans, it would pose a great threat to public health. Since its emergence in China in 2013, H7N9 has caused considerable morbidity and mortality. In the absence of a universal influenza vac...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: de Jonge, Jørgen, Isakova-Sivak, Irina, van Dijken, Harry, Spijkers, Sanne, Mouthaan, Justin, de Jong, Rineke, Smolonogina, Tatiana, Roholl, Paul, Rudenko, Larisa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881767/
https://ncbi.nlm.nih.gov/pubmed/26796670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.23
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